Antimicrobial Activities of Fidaxomicin

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Antimicrobial Activities of Fidaxomicin

Fidaxomicin is bactericidal against Clostridium difficile. The combined results of 8 in vitro studies of 1323 C. difficile isolates showed the minimum inhibitory concentration (MIC) range of fidaxomicin to be ≤ 0.001-1 μg/mL, with a maximum MIC for inhibition of 90% of organisms (MIC(90)) of 0.5 μg/mL. Isolates from 2 phase III clinical trials demonstrated that fidaxomicin MICs of baseline isol...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2012

ISSN: 1537-6591,1058-4838

DOI: 10.1093/cid/cis339